Scientists have learned how to diagnose coronary heart disease by blood test
Researchers from our University: Polyakova E.A., Zaraisky M.I., Mikhailov E.N., Baranova E.I., Galagudza M.M. under supervision of the Head of Faculty Therapy Department, Academician of the Russian Academy of Sciences Yevgeny Vladimirovich Shlyakhto made scientific discovery.
For the first time non-cholesterol markers of multivessel atherosclerosis of coronary arteries in patients with coronary heart disease (CHD) were found in the blood. Scientists have shown that levels in the blood and myocardium of certain microRNA molecules are directly associated with multivessel coronary atherosclerosis in patients with coronary heart disease. This means that with the help of a blood test, it is possible to diagnose ischemic heart disease and its severe clinical forms, such as acute coronary syndrome and myocardial heart attack. As you know, these pathologies are widespread in the world and are the main causes of mortality. The identification of markers of high cardiovascular risk is a priority task for scientists in order to prevent coronary artery disease and reduce mortality.
“For the first time, we were able to detect non-cholesterol markers in peripheral blood, indicating a high probability of multivessel atherosclerotic coronary artery disease in ischemic heart disease,” comments a senior researcher at the Research Institute of Cardiovascular Diseases, Assistant of the Faculty Therapy Department, cardiologist, Ph. M.Sc. Ekaterina Anatolyevna Polyakova. "This will greatly facilitate and speed up the diagnosis, as well as will help to start treatment before the disease becomes life-threatening."
The results of the work were published in the International Journal of Cardiology (DOI: 10.1016 / j.ijcard.2020.08.043). Polyakova EA, Zaraiskii MI, Mikhaylov EN, Baranova EI, Galagudza MM, Shlyakhto EV. Association of myocardial and serum miRNA expression patterns with the presence and extent of coronary artery disease: a cross-sectional study. Int J Cardiol 2020; р. 1-11.
